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Genicular Artery Embolization vs. Knee Gel Injections

Young Runner with Knee Pain

GAE vs. Knee Gel Injections: Which Treatment Works Better?

Genicular artery embolization (GAE) and knee gel injections are minimally invasive treatments for knee osteoarthritis, offering patients relief from chronic knee pain and improving overall function. These two procedures have gained popularity as alternative options to knee replacement surgery and have shown promising results in reducing pain and increasing mobility for patients with knee osteoarthritis.

Genicular Artery Embolization

Genicular artery embolization is a cutting-edge, minimally invasive procedure that targets the genicular arteries surrounding the knee joint. By selectively blocking these arteries, GAE reduces the inflammation and pain associated with knee osteoarthritis. The effects of GAE are often long-lasting, providing sustained relief from osteoarthritis symptoms.

  • No hospital stay
  • Same day procedure
  • Improved function and range of motion of the knee
  • Significantly reduces knee pain and inflammation
  • Symptom improvement lasting for 1 to 3 years
  • Ideal for candidates with moderate to severe osteoarthritis

Knee Gel Injections

Knee gel injections, also known as viscosupplementation, involve the injection of hyaluronic acid directly into the knee joint. Hyaluronic acid is a naturally occurring substance in the joint fluid that helps lubricate and cushion the knee, improving mobility and reducing pain. However, the effects of knee gel injections are not permanent, and only provide short-term pain relief, with some patients reporting little to no relief at all. 

  • No hospital stay
  • Same day procedure 
  • Results last 6 – 12 months
  • Temporary pain relief  
  • Repeat injections are needed to maintain pain relief
  • May not be an effective treatment for everyone
  • Ideal for candidates with mild to moderate OA
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GAE Procedure vs. Knee Gel Injections

Knee gel injections are simple, quick, and performed on an outpatient basis, avoiding the need for surgery similar to GAE. During the injection process, the knee area is cleaned and numbed, and then using a fine needle hyaluronic acid is injected into the knee joint. The injection typically takes only a few minutes and you can go home the same day. 

The GAE process begins with a detailed consultation with an interventional radiologist at American Knee Pain Centers. Imaging tests, such as MRI or X-ray, are conducted to map the blood vessels around the knee and determine the best approach for the procedure. During GAE, a tiny catheter is then inserted through a small incision, typically in the groin, and guided to the genicular arteries. Micro-sized particles are injected to block these arteries, reducing blood flow to the inflamed areas and effectively alleviating pain and inflammation. The entire procedure usually takes about 1-2 hours and is a same-day procedure similar to knee gel injections.

Throbbing Knee Pain
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Genicular Artery Embolization vs. Knee Gel Injection Recovery

The recovery time for knee gel injections is immediate to a few days. Patients may need to avoid strenuous activities for a short period but can usually resume normal activities soon after the injection. The recovery time for GAE is similar, lasting only a few days with patients being able to return to light activities within a week.

Hiker with Knee Pain

Which Knee Pain Treatment is Right For You?

Choosing between GAE and knee gel injections depends on the severity of your osteoarthritis. GAE is often more suitable for severe cases that have not responded well to other treatments, while knee gel injections are typically used for mild to moderate cases. Also, knee gel injections may not work for everyone. There have been cases where some people have not experienced significant pain relief in their knees from the injections. If you are older or have severe osteoarthritis, you may be unable to find relief from this treatment.

At American Knee Pain Centers, we recommend GAE as our preferred knee pain treatment option for patients with osteoarthritis. GAE is a minimally invasive treatment that provides long-lasting results and significant relief from osteoarthritis symptoms. It effectively improves chronic knee pain, inflammation, and range of motion – helping patients manage their symptoms for up to two years or more compared to temporary relief provided by knee injections.

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Why Choose American Knee Pain Centers for GAE?

American Knee Pain Centers is your top choice for treating chronic osteoarthritis knee pain. Our affiliated team of interventional radiologists is committed to providing minimally invasive solutions, such as GAE,  to alleviate pain, discomfort, and inflammation without the need for surgery. By choosing American Knee Pain Centers for GAE, you gain access to state-of-the-art technology and a team devoted to enhancing your quality of life through patient-centric care.

Our Knee Pain Specialists

Do you have chronic knee pain? Our board-certified interventional radiologists in New York can help treat your pain caused by osteoarthritis. They work with you to create a customized treatment plan that relieves the pain in your knees and improves your range of motion. You can find the following affiliated knee pain specialists at our offices in New York.

Find Relief at Our Knee Pain Centers in NY

With multiple outpatient centers throughout New York, American Knee Pain Centers is dedicated to providing comprehensive care for individuals suffering from knee osteoarthritis. If you are experiencing pain, swelling, or tenderness, please schedule an appointment at one of our knee pain centers in NY.

Queens, NY
30-30 Northern Blvd
Suite 501
Queens, NY 11101
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Harlem, NY
505 East 116th Street Suite 400
Harlem, NY 10029
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Brooklyn, NY
71 Carroll Street
Brooklyn, NY 11231
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What Our Patients Are Saying

Excellent staff & Dr and his assistants
Emily
Emily
21:32 25 Jun 26
I was so confident in them the nurses and the receptionist are also kind and caring about you. The Dr and his assistant were excellent. Everyone in that office was excellent. I felt very comfortable with them.
Emily Fanelli
Emily Fanelli
21:31 25 Jun 26
These Doctor’s That Works At Harlem Endovascular, What These People Had Did To My Legs, They Did A Real Great Job, And They Really Are The Best !!!
Raul Diaz
Raul Diaz
18:38 22 Jun 26
Awesome service, a beautiful staff and teamFrom booking ur appointment to receiving care. Had i known about them i know I would have been better already. I love how polite understanding and comfortable everyone make you feel it definitely make you feel better during care The services here are top notch. I know my healing journey is even greater.
Barbara Maschack
Barbara Maschack
21:31 18 Jun 26
Dr Sham is a very good doctor who helped me with everything he made sure he had they gave me something for the pain and to relax before the procedure and everything went perfect he is the best 5 star’s.
Martin Fagen
Martin Fagen
20:42 15 Jun 26
His team is excellent. Make you feel safe.
Doris Val
Doris Val
22:41 02 Jun 26
Everyone was friendly and helpful and Dr. Rivera was very focused in doing what is best for my mother.
Michael Robayo
Michael Robayo
21:15 02 Jun 26
Very good staff and doctor.
Moises Cuevas
Moises Cuevas
20:57 28 May 26
Very professional. Kept me informed through the procedure.
Laurence Clarke
Laurence Clarke
20:37 27 May 26
Great Service, they explain everything and make you feel relaxed comfortable. From the staff to the Doctor fabulous!
Janet “Jangirl212”
Janet “Jangirl212”
20:49 20 May 26
It’s been the 2nd time I have the procedure no complaint at all
fernando medina
fernando medina
13:03 20 May 26
Just wonderful!!!
Rose Grandma
Rose Grandma
23:05 14 May 26
Doctor shams and his team are very good .They took care of me and showed me that they cared how I was feeling after the procedure .i highly recommended the doctor and his staff
Maria Ortiz
Maria Ortiz
20:34 05 May 26
Dr. Shams has done 2 procedures in my left leg and had cero issues. He did a great job both times.
Roberto Rosales
Roberto Rosales
20:26 04 May 26
Experience was excellent
William Oquendo
William Oquendo
20:41 29 Apr 26
If this is pertaining to the vein specialist, they were very professional and extremely knowledgeable.
Thomas Kitchen
Thomas Kitchen
20:49 24 Apr 26
Very welcoming staff.Efficient .They didn’t try to schedule you for unnecessary procedures.
Diana Richardson
Diana Richardson
18:11 19 Apr 26
Excellent. His technical experience Is amazing in that his treatment givis you the best comfort, addressing your concern with confidence. I have chronic PAD and already undergone procedures done by him more than 20 times.
Abebe Akalu
Abebe Akalu
21:00 14 Apr 26
Good i feel fine. Thank u
Gwendolyn White
Gwendolyn White
01:31 09 Apr 26
Dr. Shams was friendly and nice. He made me feel comfortable and answered all my questions.
Osariemen Elcock
Osariemen Elcock
20:38 26 Mar 26
Very kind and polite
Trenice Taylor
Trenice Taylor
22:29 18 Mar 26
Love my visits smooth best vascular doctor
Charmaine Lawrencr
Charmaine Lawrencr
13:01 07 Mar 26
Very courteous
Catherine Quintero
Catherine Quintero
22:40 26 Feb 26
Good service; one of my family members needed an angioplasty done. The medical professionals were very thorough and explained the entire process, along with following up a couple of days afterwards to see how things were.
Charles Brewster Jr
Charles Brewster Jr
22:16 23 Feb 26
Very Professional and Caring Environment. Without any hesitation, I would recommend the Endovascular Center of Harlem.
Nikki
Nikki
22:25 10 Feb 26
P very smooth cool and pleasant experience
Peter Handras
Peter Handras
22:34 22 Jan 26
I didn’t have to wait long to see Dr Shams he checked my wound and everything looked good the nurses were very efficient and took good care of me
Lynn Brightman
Lynn Brightman
16:56 18 Jan 26
I cannot say enough great things about Dr. Joseph N. Shams and his entire team. From the moment you walk into his office, you are treated with genuine care, respect, and professionalism that truly sets this practice apart. Dr. Shams is not only extremely knowledgeable and thorough, but he also takes the time to actually listen to his patients. He explains everything clearly, answers questions patiently, and makes sure you feel comfortable and confident every step of the way.What truly makes this office exceptional is the team of nurses and staff who work alongside him. Every single person you encounter is kind, attentive, and welcoming. The nurses go above and beyond to make sure patients feel cared for, never rushed, and always supported. You can tell they genuinely love what they do, and that positive energy carries throughout the entire office.Appointments are well-organized, wait times are reasonable, and the overall environment is clean, calm, and professional. It’s rare to find a medical office where every single staff member consistently delivers such a high level of service, but Dr. Shams and his team manage to do exactly that.If you’re looking for a doctor who truly puts patients first and an office where compassion and excellence are the standard, not the exception, I highly recommend Dr. Joseph N. Shams and his incredible staff. This is healthcare done the right way.
Ken C
Ken C
03:00 16 Jan 26
Excellence all around. The doctor clearly explained the treatment and what was to be expected during recovery phase of healing.I am pleased with the outcome.The facility was clean, and the staff were very friendly. I highly recommend the. Thanks.
J B
J B
16:15 19 Dec 25
Dr. Shams is amazing. He takes his time and addresses your concerns and questions
Regina Jones
Regina Jones
22:22 05 Dec 25
The visit was great good service from everyone staffs / doctors very professional and on time I will give a 10+
Linda Noriega
Linda Noriega
23:06 25 Nov 25
Dr. Shan is a blessing sent from god. After seeing him my leg/ feet swelling was down. After being on my feet for hours. The staff were all attentive very professional. Answered any questions and concerns I had at the time. The entire team was great. I am so pleased I did my research and change Vascular doctors. You guys are all great. You make your patients fell welcome. Keep doing what you guys are doing. God bless you all.
Tina McLaughlin
Tina McLaughlin
05:52 18 Nov 25
Outstanding. Kindness, patience and excellence. Im doing well.
Deborah Moss
Deborah Moss
15:03 14 Nov 25
Dr Shams is a wonderful n caring person so is his whole staff.
Ana Rosario
Ana Rosario
17:20 12 Nov 25
I am walking much better than before and I’m not walking with a cane no more so Dr. Sam did a pretty good job on me. Thank you, Dr. sham
Sharon Gy
Sharon Gy
22:23 10 Nov 25
He show unusual compassion and skill. I was soo nervous but the center’s team & DR was Excellent!
Verian Evans-Pimble
Verian Evans-Pimble
21:16 23 Oct 25
Dr. Shams Such a amazing vascular Surgeon knows him a little while, he knows exactly what should be done to makes everything better, I’m very satisfied with my procedure and also his work ethic, the vascular office included everything inside is a 5 Star luxury, thank – you to all the staff . MoniqueV Francois.
MoniqueV Francois
MoniqueV Francois
20:55 23 Oct 25
The staff and the doctor were very professional and treated me with the best care possible.
Sargent Rivera
Sargent Rivera
20:56 17 Oct 25
Great experience
bob f
bob f
16:37 25 Sep 25
The best vascular doctor in the tri state area and a good friend
Darryl Jacobs
Darryl Jacobs
05:25 03 Sep 25
I just love the the warm smiles that you are greeted with,the professional manner iis just awesome and they never rush you through you threw a vist.I would recommend them toeveryboy
Bertha Duncan
Bertha Duncan
01:39 03 Sep 25
Staff and Dr. shams very friendly made me feel at ease. Explained to me what was wrong and what needed to be done so that I can understand.
Debra Santos
Debra Santos
22:16 02 Sep 25
Everything was perfect and professional. I am feeling fine and delighted with the results
Fred Spinowitz
Fred Spinowitz
22:12 02 Sep 25
It was great the service hope it continues
Joanna Morales
Joanna Morales
17:43 14 Aug 25
Wonderful visit. He really is the best. Do not have e to wait long a day he takes his time.
Cynthia J
Cynthia J
18:36 31 Jul 25
Dr Shams is good!!!!
David Forbes
David Forbes
18:48 24 Jul 25
I found that both the doctors and staff to be complete professionals in their practice
George Greene
George Greene
18:59 11 Jun 25
Was treated very nice by the personal
Milton williams
Milton williams
19:56 03 Jun 25
I WENT TO THE DOC, TO EXPLAIN MY ISSUES AND I LEFT FEELING BETTER THAN WHEN I WENT IN. THANK YOU DOC
Nesamiah B
Nesamiah B
20:44 06 May 25
It 1 thing to to know. The GOD HAS many to show great work. Thank you staff. I feel good . That there is feed back .Thank Angels for showing the Grace of GOD IS AT. HERE AT. PLACE.
Patt Craig
Patt Craig
20:55 23 Apr 25
Looking forward to my next appointment! Best care I’ve had in many
Deborah “Debbie”
Deborah “Debbie”
19:40 23 Apr 25
Staff, Dr Sham super 10plus
Roger Mojer
Roger Mojer
17:20 02 Apr 25
Great location.
Excelente Dr y su equipo medico, información claro que lo que a uno como paciente está experimentado altamente recomendado
A ñ Ivan Yanez
A ñ Ivan Yanez
17:51 13 Feb 25
Dr David Mobley was kind right to the point. Explained & solved my issue. The whole staff is professional.
Lizette
Lizette
17:52 03 Aug 24
I felt very comfortable with him. Excellent bedside manner, proper teaching , and knowledgeable. I highly recommend him!
Jamel Jackson
Jamel Jackson
14:07 27 Feb 24
The absolute BEST Dr!! Detailed, caring & kind! The best medical procedure I’ve ever had from consultation to post procedure, perfect! 10s all around 👏🏽👍🏽👍🏽 many thank yous🙏🏾
Josi W
Josi W
22:04 12 Jan 24
Excellent service and staff i’ll let you feel relaxing and comfortable
kadine campbell
kadine campbell
21:01 23 Oct 23
Really like this doctor, talks in your language, just over all regular nice person.
Linda Thoomey
Linda Thoomey
22:03 21 Jul 23
I’m very satisfied of my visit for the first time, everyone was concerned about me, and Dr David was very patient to listen to my long health stories, after that He gave me good explanation for my problem, that was great 👍
Claude Jean Pierre
Claude Jean Pierre
22:38 18 Jul 23
Follow up to a procedure. Dr Mobley and his staff are great and always helpful
DanLiza Diehl
DanLiza Diehl
21:25 10 Jul 23
David monkey,MD and the grupo are excellent very kind and helpful.i will return to them.the attention.its very satisfied.thank u ..
Luis Sarria
Luis Sarria
12:16 29 Jun 23
I had a good experience with my procedure and Dr. Mobley’s follow-up calls are great. I’ve never had a doctor who has been so concerned about following up after a procedure to see how I’m doing and if there are any post-procedure problems I may have experienced (which there aren’t). I’d highly recommend Dr. Mobley.
Hey Beej
Hey Beej
16:42 23 Jun 23
Dr Mobley was so helpful, informative and made me feel secure in making my future medical plan. Supportive and kind. Highly recommended.
Amanda L Browder
Amanda L Browder
15:57 23 Jun 23
Doctor was very thorough. Explaining what the procedure is all about. Tell me what I could realistically expect. Couldn’t have asked for a better consultation. Highly recommended if you have a prostate issue
John Buric
John Buric
16:26 15 Jun 23
I was very pleased and satisfied on how Dr. David Mobley examined me and explained everything on what I need to know regarding my condition. He’s very professional and knowledgeable in all aspects of his profession. I would highly recommend him to my other friends!
Celine Parcon
Celine Parcon
23:16 07 Jun 23
He puts his patients before himself, returning calls and e-mails quickly. Not only is he kind and considerate, he is an excellent physician. I had to have a procedure that requires me to be awake, and he talked me through it and kept me at ease. If I could give him more stars, I would.
Super friendly, tentative, once in the procedure rm the sx staff made you feel comfortable, easy,+ answered all questions. David mobley, MD answered all my questions, very informative, caring. I felt confident in his care
Thais Bini
Thais Bini
21:22 30 May 23
Great doctor. Everyone is so kind and caring. Great place to go
Joan Jurica
Joan Jurica
14:46 30 May 23
The best in Astoria I recommend Dr mobley and staff 100 percent
michaela1951
michaela1951
21:25 30 Mar 23
Knowledgeable , experienced, great bed side manners
mohamed hamed
mohamed hamed
10:09 30 Mar 23
The doctor was very nice and professional. He explained the tests that I need and why I need them.
Judith AndersonNeal
Judith AndersonNeal
22:12 27 Mar 23
This was the best experience I have had in such a long time and I have had quite a few procedures in the past both in patient and out including the procedure I was currently present for. No other surgeon has been so kind, transparent, and gentle. Not only did he personally come out beforehand to provide me with education on my procedure, but he talked me through every step of the way and made me feel so comfortable and relaxed. Not to mention his amazing staff! Despite being extremely nervous they kept me smiling and laughing throughout the whole process. 10/10 would recommend. Thank you so much guys!!
Riah L.
Riah L.
13:49 22 Mar 23
Excellent bedside manners and the procedure was a breeze.
sen-pei hsia
sen-pei hsia
18:26 20 Mar 23
Los mejores/ the best💖🙏
Ruthy Ochoa
Ruthy Ochoa
04:17 03 Mar 23
I went with my mom who just had a hip surgery. The whole team was very caring, nice and very professional. I did appreciate that the surgeon took the time to explain to me what was wrong with my mom’s arm and what he did to fix it.
mouna khalyat
mouna khalyat
14:37 24 Feb 23
Although I didn’t meet with the doctor, the receptionist, assistant and nurse were great.
Theresa Gaines
Theresa Gaines
13:25 13 Feb 23
Every thing and the process are being done properly ..Terissa you are very Carey ..thank you so much every body are very polite and very professional.. Thank you so much to Dr.Mobley..God blessed you all .🙏🙏🙏👍
Remigio Ruda
Remigio Ruda
03:28 31 Jan 23
Very knowledgeable, personable and professional. I came to Dr. Mobley to correct another surgeons work and I was pleased with the outcome. There is a Hispanic woman that runs things in the O.R.She is great! The whole staff is wonderful and caring.Highly recommend
Lakesha Kingdom
Lakesha Kingdom
15:57 17 Jan 23
I had a wonderful PA take care of me, & the nurses were very sweet. I was happy with my visit
Aurora Anello
Aurora Anello
19:20 10 Jan 23
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Woman Grabbing Her Knee scaled
Take the first step toward a pain-free life!

Don’t let knee pain limit your life any longer! Schedule an appointment with our specialist to start your pain-free journey today.